Process chemistry · Hard
Reaction-calorimetry safety assessment
Convert calibration pulses, blank dosing experiments, and reaction heat-flow traces into auditable run metrics, replicate summaries, and protocol-level scale-up decisions.
Every screening outcome must remain traceable to calibration, corrections, and protocol-level evidence.
Derived metrics remain linked to the corrected trace and source protocol.
Workflow
Establish calibration
Derive heat-flow sensitivity from electrical pulses and quantify blank dosing heat.
Correct the time series
Apply baseline and blank corrections while retaining run, protocol, time, feed, and event provenance.
Derive thermal metrics
Integrate released heat and calculate reaction enthalpy, adiabatic rise, accumulation, MTSR, post-feed heat, and recovery.
Screen by protocol
Summarize replicates and map each decision and reason back to declared configuration criteria.